475 research outputs found
Changing narratives: colonised peoples, criminology and social work
Abstract: There is growing recognition in criminology and social work of the importance of Indigenous knowledges and methodologies. Yet to date there have been limited attempts (particularly in criminology and criminal justice social work) to consider the theoretical and practice implications of Indigenous understandings and approaches to these disciplines. Both disciplines have also been slow to recognise the importance of understanding the way in which colonial effects are perpetuated through knowledge control, particularly in the operation of criminal justice systems.
Our paper thus begins by examining the historical and institutional factors that have contributed to the continuing subjugation of Indigenous knowledges and methodologies. A discussion of the connections between the hegemony of Western science, the construction of race, and the colonial project follows. While herein Western and Indigenous approaches are conceptualised broadly, the dangers of over-simplifying these categories is also acknowledged. The paper proceeds by examining the distinctive character of each approach through a consideration of their ontological, epistemological, axiological, and methodological differences. Whilst acknowledging the considerable challenges which arise in any attempt to develop connections between these differing worldviews, a pathway forward for understanding both theoretically and methodologically the relationship between Western and Indigenous approaches is proposed
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A hidden cost of happiness in children.
Happiness is generally considered an emotion with only beneficial effects, particularly in childhood. However, there are some situations where the style of information processing triggered by happiness could be a liability. In particular, happiness seems to motivate a top-down processing style, which could impair performance when attention to detail is required. Indeed, in Experiment 1, 10- to 11-year-old children (N = 30) induced to feel a happy mood were slower to locate a simple shape embedded in a complex figure than those induced to feel a sad mood. In Experiment 2, 6- to 7-year-old children (N = 61) induced to feel a happy mood found fewer embedded shapes than those induced to feel a sad or neutral mood. Happiness may have unintended and possibly undesirable cognitive consequences, even in childhood
Patterns of Cranial Trauma at the Akers Site (34LF32) of Southeastern Oklahoma
Previous work at Wister Valley Fourche Maline sites in southeastern Oklahoma has concluded that the area was a contested landscape with extensive feuding, resulting trophy-taking behavior, and mass burials. Preliminary paleopathological work at the Akers site (34Lf32) suggested that there may have been a high percentage of broken bones, however complete analyses had not been completed. New paleopathological work at the Akers site indicates that 35 percent of the adults buried there had at least one fractured bone at time of death. Furthermore, adult females were more likely to have lower limb fractures and multiple fractures, suggesting different patterns of stress and/or violence for at least some of the adult female population
The case studies: authentic learning
Moving from theory to practice in higher education is deeply challenging. While
exploring pedagogical models in the literature may lead to tacit understanding of
general principles, actually implementing these principles in practice can be an
entirely different matter
What impact do posters have on academic knowledge transfer? A pilot survey on author attitudes and experiences
<p>Abstract</p> <p>Background</p> <p>Research knowledge is commonly facilitated at conferences via oral presentations, poster presentations and workshops. Current literature exploring the efficacy of academic posters is however limited. The purpose of this initial study was to explore the perceptions of academic poster presentation, together with its benefits and limitations as an effective mechanism for academic knowledge transfer and contribute to the available academic data.</p> <p>Methods</p> <p>A survey was distributed to 88 delegates who presented academic posters at two Releasing Research and Enterprise Potential conferences in June 2007 and June 2008 at Bournemouth University. This survey addressed attitude and opinion items, together with their general experiences of poster presentations. Descriptive statistics were performed on the responses.</p> <p>Results</p> <p>A 39% return was achieved with the majority of respondents believing that posters are a good medium for transferring knowledge and a valid form of academic publication. Visual appeal was cited as more influential than subject content, with 94% agreeing that poster imagery is most likely to draw viewer's attention. Respondents also believed that posters must be accompanied by their author in order to effectively communicate the academic content.</p> <p>Conclusion</p> <p>This pilot study is the first to explore perceptions of the academic poster as a medium for knowledge transfer. Given that academic posters rely heavily on visual appeal and direct author interaction, the medium requires greater flexibility in their design to promote effective knowledge transfer. This paper introduces the concept of the IT-based 'MediaPoster' so as to address the issues raised within published literature and subsequently enhance knowledge-transfer within the field of academic medicine.</p
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Validation of the new pathology staging system for progressive supranuclear palsy
Progressive supranuclear palsy (PSP) is a neurodegenerative disorder associated with neuroglial accumulation of 4-repeat tau protein [2]. Kovacs et al. [1] have recently proposed a new semi-quantitative six-stage system to categorise the severity of PSP pathology. Importantly, the system reduces reliance on regions with high risk of concomitant pathology and focusses on cell type specific tau-pathology.Cambridge Centre for Parkinson-plus (RG95450), and the NIHR Cambridge Biomedical Research Centre (BRC-1215-20014).
The Cambridge Brain Bank is supported by the NIHR Cambridge Biomedical Research Centre
Association between Knops blood group polymorphisms and susceptibility to malaria in an endemic area of the Brazilian Amazon
Complement receptor 1 (CR1) gene polymorphisms that are associated with Knops blood group antigens may influence the binding of Plasmodium parasites to erythrocytes, thereby affecting susceptibility to malaria. The aim of this study was to evaluate the genotype and allele and haplotype frequencies of single-nucleotide polymorphisms (SNPs) of Knops blood group antigens and examine their association with susceptibility to malaria in an endemic area of Brazil. One hundred and twenty-six individuals from the Brazilian Amazon were studied. The CR1-genomic fragment was amplified by PCR and six SNPs and haplotypes were identified after DNA sequence analysis. Allele and haplotype frequencies revealed that the Knb allele and H8 haplotype were possibly associated with susceptibility to Plasmodium falciparum. The odds ratios were reasonably high, suggesting a potentially important association between two Knops blood antigens (Knb and KAM+) that confer susceptibility to P. falciparum in individuals from the Brazilian Amazon
Atheisms and the purification of faith
Philosophers of religion have distinguished between ‘negative’ and ‘positive’ atheism. This article considers further conceptions of atheism, especially the idea that atheism can facilitate a faith in God purified of idolatrous assumptions. After introducing Bultmann’s contention that a ‘conscious atheist’ can find something transcendent in the world, this contention is interpreted through reflection on Ricoeur’s claim that the atheisms of Nietzsche and Freud serve to mediate a transition to a purified faith – a faith involving heightened receptivity to agapeic love. The troubling question of what differentiates atheism from belief in God is then discussed in the light of Simone Weil’s meditations on God’s secret presence
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Locus coeruleus pathology in progressive supranuclear palsy, and its relation to disease severity
Abstract: The locus coeruleus is the major source of noradrenaline to the brain and contributes to a wide range of physiological and cognitive functions including arousal, attention, autonomic control, and adaptive behaviour. Neurodegeneration and pathological aggregation of tau protein in the locus coeruleus are early features of progressive supranuclear palsy (PSP). This pathology is proposed to contribute to the clinical expression of disease, including the PSP Richardson’s syndrome. We test the hypothesis that tau pathology and neuronal loss are associated with clinical heterogeneity and severity in PSP. We used immunohistochemistry in post mortem tissues from 31 patients with a clinical diagnosis of PSP (22 with Richardson’s syndrome) and 6 control cases. We quantified the presence of hyperphosphorylated tau, the number of pigmented cells indicative of noradrenergic neurons, and the percentage of pigmented neurons with tau-positive inclusions. Ante mortem assessment of clinical severity using the PSP rating scale was available within 1.8 (±0.9) years for 23 patients. We found an average 49% reduction of pigmented neurons in PSP patients relative to controls. The loss of pigmented neurons correlated with disease severity, even after adjusting for disease duration and the interval between clinical assessment and death. The degree of neuronal loss was negatively associated with tau-positive inclusions, with an average of 44% of pigmented neurons displaying tau-inclusions. Degeneration and tau pathology in the locus coeruleus are related to clinical heterogeneity of PSP. The noradrenergic deficit in the locus coeruleus is a candidate target for pharmacological treatment. Recent developments in ultra-high field magnetic resonance imaging to quantify in vivo structural integrity of the locus coeruleus may provide biomarkers for noradrenergic experimental medicines studies in PSP
Socioeconomic status and antisocial behaviour among children and adolescents: A systematic review and meta-analysis
Previous research on the association between socioeconomic status (SES) and child and adolescent antisocial
behaviour has produced mixed findings showing variation in the strength of association. This systematic review
and meta-analysis aimed to summarise evidence on the relationship between socioeconomic status and broadly
conceptualised antisocial behaviour, investigating variation across a range of antisocial subtypes and other potential
moderators, including age, sex and informant. We identified 133 studies containing data suitable for effect
size calculation, and 139 independent effect sizes were analysed (total N = 339868). The global meta-analysis
showed that lower family socioeconomic status was associated with higher levels of antisocial behaviour. Moderation
analyses revealed this relationship was stronger where callous–unemotional traits were the outcome,
and where antisocial behaviour was reported by parents or teachers rather than self-reported. The relationship
between family SES and antisocial behaviour, however, was independent of higher-level constructs such as national
income inequality. These results indicate that SES can be considered a robust correlate of broadly
conceptualised antisocial behaviour but the strength of this relationship may depend on the antisocial subtype
under investigation and the design of the stud
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